How We Know the COVID-19 Vaccine is Safe
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This blog was originally published on December 22. For the latest COVID-19 vaccination information, including which groups are currently eligible, visit our vaccine page.
There’s a lot of information about the COVID-19 vaccines to keep up with. In previous blog posts, we’ve explained the process of developing and authorizing the first COVID-19 vaccine for use, and who will get the vaccine first and why. You probably have questions about the safety of the vaccine. Here are the facts:
Safety during vaccine development and trials was a top priority
No phases of vaccine development or testing were skipped
All vaccines, when developed, go through trial phases. In those phases, the researchers recruit volunteers to try the vaccine. The phases help determine if the vaccine is safe and if there are any serious side effects. The COVID-19 vaccine process moved quickly, but no phases were skipped and were as rigorous as usual. In total, the Pfizer vaccine had over 44,000 volunteers participate in the trials and trial volunteers were monitored for a minimum of two months following vaccination.
Safety monitoring doesn’t stop when a vaccine is authorized or approved. The FDA and CDC closely monitor vaccine safety after the public begins to use a vaccine. They watch for possible side effects and adverse events. This ensures they identify any possible risks associated with the vaccine.
Volunteers were protected
After centuries of medical abuse in our country, there are now rules to ensure that companies and the US government do not test medical treatments on people without their consent. In order for a vaccine to be approved or authorized by the Food and Drug Administration (FDA), an Institutional Review Board (IRB) made up of researchers not connected to the vaccine assures that steps are taken to protect the rights and welfare of the people participating in the research.
Representation is important
The Pfizer and Moderna vaccine trials included people of various racial and ethnic groups. For the Pfizer vaccine in particular, approximately 42% of overall and 30% of US trial volunteers were non-white. In the Moderna trials, people of color made up around 37% of volunteers.
The vaccine is safe
No specific safety concerns were found
In the Emergency Use Authorization (EUA) for both the Pfizer and Moderna vaccine, FDA analysis of the vaccines says they found "no specific safety concerns identified that would preclude issuance of an EUA."
When looking at the incidence of serious adverse events for the Pfizer vaccine, it was extremely low, and similar for both the volunteers who received vaccine and those who received a placebo, at 0.6% and 0.5% respectively.
You can’t get COVID-19 from the COVID-19 vaccine
The Pfizer and Moderna vaccines that have been authorized don’t use the live virus that causes COVID-19. As a matter of fact, they don’t contain the virus at all.
About 30 years ago, scientists began developing a new kind of vaccine, using Messenger RNA (mRNA). When the pandemic began, scientists had already been hard at work on the new technology. They have used the gene structure of the virus to create the right mRNA sequence for the vaccine.
mRNA is not able to alter or modify your genetic makeup (DNA).
Former CDC director Dr. Tom Frieden explained it like this: mRNA is like an email that tells your immune system "what the virus looks like, instructions to kill it, and then – like a Snapchat message – it disappears." The CDC has more information about mRNA vaccines.
You may experience some side effects that seem like symptoms of COVID-19, like headache or fever after you get your vaccines. It doesn’t mean the vaccine gave you the virus. It’s normal, and it means your body is building immunity to the virus. This is a great explanation on how COVID-19 vaccines work.
Just like with a flu shot, it takes a little while for your body to build up full immunity after you get vaccinated. While you are waiting, you’re not fully protected and could actually get sick with the virus. This is part of the reason that it’s so important to keep doing all the protective measures you’ve been doing, like wearing a mask and washing hands often, even after you’ve gotten your vaccines.
Some side effects are to be expected
As we mentioned above, it’s normal to feel some mild to moderate side effects after you get your COVID-19 vaccine. It’s a sign your body is building up immunity to the virus.
The most common side effects include pain and swelling where you got the shot, fever, chills, tiredness, and headache. You may feel a little like you have the flu. It’s a normal reaction, and the side effects typically last just a day or two. The CDC has great information on what to expect for side effects and how to deal with them.
Unexpected adverse events get reported
We explained the normal possible side effects you may have after getting your vaccine. So what is an adverse event? In short, it’s any health problem that happens after someone gets a vaccine. It could be a true reaction to the vaccine, like a side effect, or it might be a coincidence that the health problem happened to occur after the vaccine was given, but isn’t caused by the vaccine. We like this explanation of adverse events from the CDC.
We explained earlier how the CDC and FDA will continue to monitor COVID-19 vaccines for safety concerns. Individuals are also encouraged to report adverse events. Safety of these vaccines is a top priority, and reporting adverse events helps the CDC monitor the safety of the vaccines. We like this explanation of the difference between a side effect and an adverse event, and encourage you to check it out.
Healthcare providers are required to report certain adverse events to a national system when they see them after providing vaccines. They also have to stick to any revised safety reporting requirements that are spelled out in the Emergency Use Authorization (EUA) of the vaccine.
The CDC is using something new to check in on your health after you get a COVID-19 vaccine. It’s a tool for your smartphone called v-safe. If you enroll to use v-safe, you can report adverse events or side effects and get a reminder for your second dose of the vaccine!
People with a history of severe allergic reaction
If you have a known history of a severe allergic reaction (anaphylaxis) to the components of the COVID-19 vaccine, talk to your healthcare provider about your risks.
Add COVID-19 vaccines to your pandemic toolbox
It’s important to use trusted sources of information when making health decisions. Websites like the CDC present the facts and are updated regularly as new information is known. We promise to keep you updated as we learn more!
Adding 2 doses of COVID-19 vaccine, when it’s available to you, is one more tool to add to the toolbox you’ve been using to protect yourself from COVID-19. Please be patient as vaccines are rolled out, and while you wait, use everything in your toolbox to keep yourself and your loved ones safe, including:; wearing a mask, washing hands often, keeping distance, avoiding gathering, and staying home with you’re sick. Just as we can’t build a house with just a hammer, we can’t end the pandemic with just one of these tools. We need them all to get there.
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- Providing Support to People in Isolation Helps Prevent the Spread of COVID-19
- Data Notes for the Week of December 3
- Tips for A Healthier Holiday Season
- Data Notes for the Week of November 25
- What COVID-19 Testing Can and Can't Tell Us
- Data Notes for the Week November 19
- What's Allowed in Emergency Order #10?
- Public Health Madison & Dane County Issues New Emergency Order #10
- Socializing More Safely This Winter: How To Form A Bubble or Pod
- How to See Family and Friends More Safely Over the Holidays
- Understanding Close Contact
- Data Notes for the Week of November 12
- When to Isolate, When to Quarantine
- Data Notes for the Week of November 5
- Employer Notification Of Employees With COVID-19
- Data Notes for the Week of October 29
- Data Notes for the Week of October 22
- Understanding ‘Clusters’
- Statewide Database Down for Planned Maintenance: October 16-18
- Data Notes for the Week of October 15
- These Next Few Weeks are a Pivotal Moment for Our County and Our State
- Data Notes for the Week of October 8
- Data Notes for the Week of October 1
- Understanding Percent Positivity
- Data Notes for the Week of September 24
- How We're Assessing if UW Cases have Spread Beyond Campus
- Data Notes for the Week of September 17
- Public Health Madison & Dane County and the City of Madison Police Department are Partnering to Increase Compliance with Public Health Orders
- Data Notes for the Week of September 10
- Community Update Following Spike in Cases of COVID-19
- UW, Public Health act to stop COVID-19 spread in fraternity, sorority houses
- Data Notes for the Week of September 3
- Data Notes for the Week of August 27
- Data Notes for the Week of August 20
- Health is a Human Right and We All Play a Role
- Data Snapshot Coming on August 20
- How We Have Made Decisions During the COVID-19 Pandemic
- Data Notes for the Week of August 10
- COVID-19 Contact Tracing: When Public Health Calls and When It’s a Scam
- Data Notes for the Week of August 3
- Data Notes For the Week of July 27
- We Can All Be Part of the Solution to the Pandemic
- Data Notes for the Week of July 20
- Data Notes for the Week of July 13
- Data Notes for the Week of July 6
- How to Lower Your Risk While Celebrating 4th of July
- Protests are not currently associated with Dane County's rise in COVID-19 cases
- Data Notes for the Week of June 29
- A Day in the Life of the Data Team
- Data Notes for the Week of June 22
- Help Break the Chain of COVID-19 Transmission--Your Actions Affect Others
- Inequities Evident in Dane County COVID-19 Data
- Understanding the Big Picture: Trends in Data Provide Perspective
- Stay the Course to Get to the Finish Line
- Coronavirus is here and it’s spreading
- Press Conference Remarks from 3/23
- How We Can Prepare for the Spread of Coronavirus (COVID-19)
- Our Role in Monitoring the Coronavirus Outbreak
- Hunger Knows No Season
- One in Five Wisconsin High Schoolers Vape—A Public Health Crisis
- Why You Should Get a Flu Vaccine This Year
- Vaccines Protect You, and Our Community
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